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X-WR-CALNAME:Center for Behavior, Evolution, and Culture
X-ORIGINAL-URL:https://bec.ucla.edu
X-WR-CALDESC:Events for Center for Behavior, Evolution, and Culture
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DTSTART;TZID=America/Los_Angeles:20231002T120000
DTEND;TZID=America/Los_Angeles:20231002T133000
DTSTAMP:20260503T044257
CREATED:20230921T195335Z
LAST-MODIFIED:20231019T201745Z
UID:6840-1696248000-1696253400@bec.ucla.edu
SUMMARY:Barbara Natterson-Horowitz - The 600-million-year history of human affective disorder
DESCRIPTION:The 600-million-year history of human affective disorder\nBarbara Natterson-Horowitz\nDivision of Cardiology\, UCLA School of Medicine\nDepartment of Ecology and Evolutionary Biology\, UCLA\nDepartment of Human Evolutionary Biology\, Harvard University\nDepartment of Global Health and Social Medicine\, Harvard Medical School\nFifty years ago this October\, the Nobel Prize in Medicine was awarded to three animal behaviorists based on the belief that the emerging field of ethology could transform our understanding of human biobehavioral health. Unfortunately\, the promise was not realized within the lifetimes of the scientists themselves. In the decades that followed\, advances in biological psychiatry challenged psychoanalysis as the singular source of explanatory insights into mental illness. Regrettably\, highly reductive biological approaches that lack a broader\, integrated organismal and ecological context have not led to much needed transformational knowledge. \nToday\, broadly comparative and ecologically-informed studies of animal behavior are revealing: 1) the ancient origins of human affective systems and affective disorders in the social brain networks of early social animals\, 2) the important links between brain biology promoting adaptive behavior in chronically subordinated animals and neurovegetative symptoms in depressed human beings\, and 3) evidence that withdrawn behavior\, anhedonia\, and reduced cognitive and motoric activity in chronic subordinates increases survival in certain individuals. Recent studies connecting social defeat to severe depression point\, once again\, to animal behavior as a source of insights into human mental health. In fact\, phylogenetic perspectives can provide much needed scaffolding on which to layer\, with context\, the rapidly growing body of reductive knowledge about the human brain in health and illness. \nDr Natterson-Horowitz’s lecture will first survey the historical and scientific settings in which both insights were recognized and overlooked. She will then present an up-to-date summary of insights into human affective disorders emerging at the intersection of behavioral ecology\, neurobiology\, psychopharmacology\, and evolutionary biology.
URL:https://bec.ucla.edu/event/barbara-natterson-horowitz-the-600-million-year-history-of-human-affective-disorder/
LOCATION:352 Haines Hall
CATEGORIES:2023,Past Presentation,Presentation
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231016T120000
DTEND;TZID=America/Los_Angeles:20231016T133000
DTSTAMP:20260503T044257
CREATED:20230921T222739Z
LAST-MODIFIED:20231019T201655Z
UID:6846-1697457600-1697463000@bec.ucla.edu
SUMMARY:Caleb Finch - The Gero-Exposome\, a life history approach to diversity of human longevity
DESCRIPTION:The Gero-Exposome\, a life history approach to diversity of human longevity\nCaleb Finch\, PhD\nARCO and Kieschnick Professor\, Leonard Davis School of Gerontology\, USC\nFrom egg to exit\, human life history is determined by environmental interactions with our genome (GxE). The Gero-Exposome provides a framework for analyzing GxE interactions with life style\, biomes\, and systemic factors. Lifespans difference of 15 years across the socio-economic status (SES) have corresponding differences in the onset of cardiovascular disease and dementia. Moreover\, SES influences the development of brain and vasculature\, by greater gestational exposure to air pollution and cigarette smoke in low SES. Multiple postnatal phases have environmental influences throughout the lifespan. As an experimental model for these complexities\, mice were gestationally exposed to air pollution. Young adults had more body fat and glucose intolerance\, while brains had lower levels of hypothalamic neuropeptides and neuronal stem cells in the hippocampus. These findings are relevant to the multi-generational stability of SES differences in health and lifespan\, for which the GxE basis is undefined.
URL:https://bec.ucla.edu/event/caleb-finch-the-gero-exposome-a-life-history-approach-to-diversity-of-human-longevity/
LOCATION:352 Haines Hall
CATEGORIES:2023,Past Presentation,Presentation
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231023T120000
DTEND;TZID=America/Los_Angeles:20231023T133000
DTSTAMP:20260503T044257
CREATED:20230925T173712Z
LAST-MODIFIED:20231024T232020Z
UID:6851-1698062400-1698067800@bec.ucla.edu
SUMMARY:Bridget Callaghan - Intergenerational impacts of adversity on mind-body health: pathways through interoception and the gut-brain axis
DESCRIPTION:Intergenerational impacts of adversity on mind-body health – pathways through interoception and the gut-brain axis\nBridget Callaghan\nAssistant Professor\, Department of Psychology\, UCLA\nChildren’s early experiences with caregivers impact their mental and physical health across the lifespan. Such early caregiving experiences can become biologically and psychologically embedded within an individual\, contributing to intergenerational transmission of adversity. My research program investigates the neurobiological mechanisms via which early caregiving experiences impact children’s mental and physical health\, and how those experiences may be transmitted to impact future generations. I will present data from several studies demonstrating how early life adversity gets ‘under the skin’ to influence children’s emotional health and physical health\, paying particular attention to gastrointestinal distress\, which is tightly connected to emotional wellbeing. Zooming in on the gastrointestinal and oral microbiomes\, I will show how adversity impacts biological systems tied to emotional and physical wellbeing. Finally\, I will show that mind-body adaptations to the state of pregnancy\, through changing interoception\, may be one pathway through which experiences of adversity are perpetuated across generations.
URL:https://bec.ucla.edu/event/bridget-callaghan-intergenerational-impacts-of-adversity-on-mind-body-health-pathways-through-interoception-and-the-gut-brain-axis/
LOCATION:352 Haines Hall
CATEGORIES:2023,Past Presentation,Presentation
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20231030T120000
DTEND;TZID=America/Los_Angeles:20231030T133000
DTSTAMP:20260503T044257
CREATED:20230925T174018Z
LAST-MODIFIED:20231107T233018Z
UID:6856-1698667200-1698672600@bec.ucla.edu
SUMMARY:Katie Karlsgodt - Reward and Cognitive Function in Adolescent Psychopathology
DESCRIPTION:Reward and Cognitive Function in Adolescent Psychopathology\nKatie Karlsgodt\nUCLA Departments of Psychology and Psychiatry\nAdolescence is a time when exploration\, and even risk-taking\, can be considered an adaptive part of the typical developmental experience. This period of enhanced risk-taking allows for new learning\, particularly about the social world\, and is a critical part of establishing independence. Risk-taking is a complex behavior\, often considered to rely on many factors\, including reward sensitivity and reward behaviors\, response to punishment\, and executive function skills that allow the balancing of competing factors and the selection of choices. However\,  in addition to being a time of exploration and independence\, adolescence is also the period of onset for many psychological disorders including schizophrenia and depression. Many such disorders include alterations in both reward and executive function\, which has the potential to impact learning and exploration during this time\, with ultimate effects on social function\, and long term daily life function. In this talk\, I will address the existing literature in this area\, recent relevant work from my lab on reward function\, adolescence\, and psychopathology\, and future directions.
URL:https://bec.ucla.edu/event/katie-karlsgodt-reward-and-cognitive-function-in-adolescent-psychopathology/
LOCATION:352 Haines Hall
CATEGORIES:2023,Past Presentation,Presentation
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