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DTSTART;TZID=America/Los_Angeles:20230206T120000
DTEND;TZID=America/Los_Angeles:20230206T133000
DTSTAMP:20260612T075424
CREATED:20221119T163213Z
LAST-MODIFIED:20230127T121720Z
UID:6694-1675684800-1675690200@bec.ucla.edu
SUMMARY:Sriram Sankararaman\, The role of archaic admixture in human evolution
DESCRIPTION:Dr. Sriram Sankararaman \nUCLA Departments of Computer Science\, Human Genetics\, and Computational Medicine \nhttp://web.cs.ucla.edu/~sriram/ \nThis talk will be in person as well as being accessible via Zoom. \nTitle: The role of archaic admixture in human evolution \n                                                                                                                                                                                                     \nAbstract: Over the past decade\, the ability to sequence genomes from both present-day   \nand archaic humans (including our closest evolutionary relatives\, the Neanderthals) has transformed our understanding of human history. Analyzing these genome sequences paints a picture of human history in which present-day humans migrated out of Africa but exchanged genes with multiple archaic human populations. I will describe statistical methods that identify segments of DNA inherited from archaic humans that are surviving in our genomes today and how these maps of introgressed archaic DNA are providing insights into human migration and biology.  Despite this progress\, our understanding of the contribution of archaic introgression to populations in Africa remains limited\, in part due to the challenges in obtaining ancient DNA in Africa. Leveraging recently developed approaches that enable inferences about archaic populations without access to their genome sequences\, we show that west African populations today inherit substantial genetic ancestry from an as-yet-unidentified archaic ghost population that diverged prior to the split of modern humans and Neanderthals. Finally\, we combine maps of introgressed Neanderthal DNA with phenotypic datasets collected in hundreds of thousands of individuals to assess the contribution of introgressed Neanderthal DNA to complex traits.    \nZoom: https://ucla.zoom.us/j/92826436236?pwd=SytQNTNPSWdwaDNlTm05d2srdXNHUT09 \nMeeting ID: 928 2643 6236 \nPasscode: BEC
URL:https://bec.ucla.edu/event/sriram-sankararaman-title-tba/
LOCATION:CA
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230213T120000
DTEND;TZID=America/Los_Angeles:20230213T133000
DTSTAMP:20260612T075424
CREATED:20221119T162059Z
LAST-MODIFIED:20221119T162059Z
UID:6685-1676289600-1676295000@bec.ucla.edu
SUMMARY:Tina Lasisi: Hair\, skin\, and the racialization of human variation.
DESCRIPTION:Dr. Tina Lasisi\, Quantitative and Computational Biology\, USC \nhttps://anth.la.psu.edu/research/research-labs/jablonski-lab/dr-tina-lasisi/ \nDr. Lasisi will present in person\, as well as via Zoom. \nTitle: Hair\, skin\, and the racialization of human variation. \nAbstract: After decades of broadcasting the message that race is a social construct\, we find uncritical taxonomic groupings of humans creep back into discussions across disciplines. The terms “race\,” “ethnicity\,” and “ancestry group” are used alongside typological descriptors of traits like skin and hair\, often distorting their variability in a way that reinforces racial typologies. The adoption of quantitative phenotyping  methods vastly improved our understanding of skin pigmentation and its evolutionary function while providing a novel non-racialized vocabulary for discussing variation in this trait. The study of hair lags behind in the exploration of phenotypic variation with a similar level of complexity. This talk will discuss the impact of methods and racialized perceptions on our understanding of the evolutionary biology of various traits and the implications of this knowledge in healthcare\, forensics\, and emerging technologies. \nZoom: https://ucla.zoom.us/j/92826436236?pwd=SytQNTNPSWdwaDNlTm05d2srdXNHUT09 \nMeeting ID: 928 2643 6236 \nPasscode: BEC
URL:https://bec.ucla.edu/event/tina-lasisi-hair-skin-and-the-racialization-of-human-variation/
LOCATION:352 Haines Hall
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230227T120000
DTEND;TZID=America/Los_Angeles:20230227T133000
DTSTAMP:20260612T075424
CREATED:20221119T164429Z
LAST-MODIFIED:20230127T122427Z
UID:6697-1677499200-1677504600@bec.ucla.edu
SUMMARY:Ainash Childebayeva: Population Genetics and Signatures of Selection in Early Neolithic European Farmers
DESCRIPTION:Dr. Ainash Childebayeva \nDept of Biological Anthropology\, University of Kansas \nWe are hoping that this talk will be both in person and via Zoom. \nTitle: Population Genetics and Signatures of Selection in Early Neolithic European Farmers \nAbstract: Throughout our evolutionary history\, humans have encountered different environmental and cultural changes that left a mark in our genomes. One such event is associated with the transition from hunting and gathering to a more sedentary farming lifestyle\, also known as the Neolithic transition. In the last ten years\, human expansion and migration in the course of the Neolithic transition in western Eurasia has been one of the major topics in ancient DNA research. Studies have shown that the spread of agriculture from the Near East to Europe was associated with a large-scale human migration. The changes in subsistence and lifestyle associated with the Neolithic\, and specifically a more sedentary lifestyle\, living in larger groups\, and the change in the diet\, have been hypothesized to involve genetic adaptation as well. I will present genome-wide ancient DNA results from an early Neolithic farming community from Central Germany\, together with available published data. The genetic profile of the Neolithic farmers of Europe shows a primarily Anatolian Neolithic-like ancestry with a small degree of admixture with the local hunter-gatherers. Moreover\, genetic data show that the Neolithic farmers of Central Germany lived in large communities that did not show strong signatures of either patri- or matrilocality. Increasing the cohort size of the early farmers to almost 100 individuals made it possible to perform frequency- and haplotype-based scans of selection. Based on the results of the test\, selection signals in pathways linked to metabolism and immune system especially stood out\, suggesting the effect of the cultural transition on the genomes of the early farmers. These findings shed light on the evolutionary pressures\, such as infectious disease and changing diet\, that were faced by the early farmers of Western Eurasia. \nZoom: https://ucla.zoom.us/j/92826436236?pwd=SytQNTNPSWdwaDNlTm05d2srdXNHUT09 \nMeeting ID: 928 2643 6236 \nPasscode: BEC
URL:https://bec.ucla.edu/event/ainash-childebayeva-title-tba/
LOCATION:CA
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